uric acid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T41242	Uric acid sodium		Reactive Oxygen Species
	Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc...		Reactive Oxygen Species
T20545	Benzarone	Benzarona,Vasoc,Venagil,Benzaronum	OAT
	Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.		OAT
T2397	Topiroxostat	FYX-051	P450 , ROS , Xanthine Oxidase
	Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.		P450 , ROS , Xanthine Oxidase
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite
T15251	Etebenecid	Urelim	Others
	Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.		Others
T21302	UNC569	UNC 569	TAM Receptor
	UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...		TAM Receptor
T79854	Lingdolinurad		OAT
	Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.		OAT
T5987	Potassium oxonate	Oxonic Acid (potassium salt),Potassium otastat,Potassium azaorotate	Others
	Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.		Others
T60625	Tigulixostat
	Tigulixostat is a novel derivative of (indolyl)heteroarylcarboxylate. Tigulixostat is a non-purine selective xanthine oxidase inhibitor, which lowers the uric acid production[1]
T15160	Dotinurad	(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone	OAT
	Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).		OAT
T21469	Cyclopenthiazide	Cyclomethiazide,Su-8341,SU 8341	Others
	Cyclopenthiazide (Cyclomethiazide) is a thiazide diuretic used to treat hypertension and heart failure. It decreases the excretion of calcium ions and uric acid and increases the excretion of sodium and potassium ions.		Others
T6875	Lesinurad	RDEA594	OAT
	Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with seru...		OAT
T61048	Puliginurad	YL-90148	OAT
	Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can be used for the prevention and treatment of hyperuricemia a...		OAT
T1362	Hypoxanthine	6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin	Others , Endogenous Metabolite
	Hypoxanthine (Purin-6-ol), also known as purine-6-ol or Hyp. Hypoxanthine is a naturally occurring purine derivative and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the...		Others , Endogenous Metabolite
T26619	Amitivir	LY217896,LY 217896,LY-217896	Others , Influenza Virus
	Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffe...		Others , Influenza Virus
T77517	URAT1 inhibitor 7		OAT
	URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 μM.URAT1 inhibitor 7 can be used to study hyperuricemi...		OAT
T0665	Xanthine	2,6-Dihydroxypurine,Isoxanthine	Endogenous Metabolite , Adenosine Receptor
	Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in...		Endogenous Metabolite , Adenosine Receptor
T0256	Citric acid trilithium salt tetrahydrate	Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate	Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways...
T0782	Benzthiazide	Aquatag,Lemazide,Dihydrex	Carbonic Anhydrase
	Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ...		Carbonic Anhydrase